Drug that blocks the action of proteasomes, cellular complexes that break down proteins.
Sinónimos
Examples for "proteasome inhibitor"
Examples for "proteasome inhibitor"
1The proteasome inhibitor bortezomib is an efficacious apoptotic agent in many tumor cells.
2Bortezomib is the first proteasome inhibitor drug tested in human patients.
3However, a significant proportion of patients who receive a proteasome inhibitor-containing regime show cardiotoxicity.
4Therefore, the proteasome inhibitor MG132 should be further evaluated for combination therapy with TRAIL.
5The introduction of proteasome inhibitor and immunomodulatory drugs has considerably changed the treatment paradigm of multiple myeloma.
1That system is a target for anticancer strategies by using proteasome inhibitors.
2Nevertheless, the mechanisms of apoptosis induced by proteasome inhibitors remain unclear.
3Both Kyprolis and Velcade are members of a class known as proteasome inhibitors.
4Overall, these findings suggest proteasome inhibitors as potential latency reversing agents.
5Overall, we determined the unique and novel mechanism of FOXM1 suppression by proteasome inhibitors.
Translations for proteasome endopeptidase complex inhibitors